Brevet : EP2233501 - ANTICORPS MONOCLONAL ANTI-CD34 HUMANISÉ, SA PRÉPARATION ET SES UTILISATIONS
Titre
ANTICORPS MONOCLONAL ANTI-CD34 HUMANISÉ, SA PRÉPARATION ET SES UTILISATIONS
N° et date de publication de la demande
EP2233501 - 29/09/2010
Type de la demande
A1
N° et date de dépôt
EP08865354.8 - 03/12/2008
N° et date de priorité
CN200710094456 - 13/12/2007 ; CN200810043016 - 08/01/2008
Classification CIB
C07K 16/28 ; A61K 39/44 ; A61P 7/06 ; A61P 35/00 ; C12N 15/13 ; C12P 21/08 ; G01N 33/543 ; G01N 33/569 ; G01N 33/574
Classification CPC
C07K 16/2896 ; C07K2317/24 ; C07K2317/56 ; C07K2317/565 ; C07K2317/92 ; G01N 33/54326 ; G01N 33/56972 ; G01N 33/57426 ; G01N2333/70596 ; G01N2800/245 ; C07K2317/76 ; A61P 35/00 ; A61P 7/06 ; G01N 33/56972 ; C07K2317/565 ; C07K2317/92 ; C07K 16/2896 ; G01N2333/70596 ; C07K2317/56 ; G01N 33/57426 ; G01N 33/54326 ; G01N2800/245 ; C07K2317/24 ; C07K2317/76
Famille de brevets
BRPI0821211A2 ; US2010311955A1 ; JP2011505810A ; EP2233501A1 ; WO2009079922A1 ; CA2708407A1
Abrégé
The present invention provides a humanized anti-human CD34 antibody and the preparation method thereof. The humanized anti-human CD34 antibody retains the affinity and specificity of its original murine-derived antibody. The antibody can be conjugated with magnetic nano materials to prepare immunomagnetic beads to screen marrow hemopoietic stem cells. It can effectively reduce the incidence rate of HAMA and improve the security of clinical transplantation of hemopoietic stem cells and can be used in treatment of certain malignant hematologic diseases and solid tumors.
INTERVENANTS
Déposant
SHANGHAI GUOJIAN BIO-TECH INSTITUTE - NO.399 LIBING ROAD ZHANGJIANG HIGH-TECH PARK SHANGHAI 201203 - CN
Titulaire
SHANGHAI GUOJIAN BIO-TECH INSTITUTE - NO.399 LIBING ROAD ZHANGJIANG HIGH-TECH PARK SHANGHAI 201203 - CN
Inventeur
GUO, YAJUN SHANGHAI 201203 - CN
QIAN, WEIZHU SHANGHAI 201203 - CN
HOU, SHENG SHANGHAI 201203 - CN
LI, BOHUA SHANGHAI 201203 - CN
WANG, HAO SHANGHAI 201203 - CN
MA, JING SHANGHAI 201203 - CN
Mandataire
HOIBERG P/S - ADELGADE 12 1304 COPENHAGEN K - DK
STATUT EN FRANCE : Dossier déchu définitivement
Délivrance
11/07/2012
Date de constatation de déchéance
-
30/08/2013 (BOPI 2013-39)