Brevet : EP1025211 - GENE DE LA SYNTHASE DE L'HYALURONAN ET UTILISATION DE CE GENE
Titre
GENE DE LA SYNTHASE DE L'HYALURONAN ET UTILISATION DE CE GENE
N° et date de publication de la demande
EP1025211 - 09/08/2000
Type de la demande
A2
N° et date de dépôt
EP98957450.4 - 30/10/1998
N° et date de priorité
US6443597 - 31/10/1997 ; US17885198 - 26/10/1998
Classification CIB
C12N 15/09 ; A61K 31/715 ; A61K 31/728 ; A61K 39/102 ; A61P 43/00 ; C12N 1/21 ; C12N 9/10 ; C12N 15/54 ; C12N 15/70 ; C12P 19/04 ; C12P 19/26 ; C12P 21/00 ; C12Q 1/68 ; C12R 1/46
Classification CPC
A61K 39/102 ; C07H 21/04 ; C08B 37/0072 ; C12N 9/1051 ; C12P 19/04 ; C12P 19/26 ; Y10S 435/839 ; Y10S 435/836 ; Y10S 435/848 ; A61P 31/00 ; A61P 43/00 ; C12N 15/52 ; C12P 19/26 ; C12N 9/1051 ; C07H 21/04 ; C08B 37/0072 ; A61K 39/102 ; C12P 19/04 ; Y10S 435/848 ; Y10S 435/839 ; Y10S 435/836
Abrégé
An isolated enzymatically-active hyaluronan synthase (HAS) is provided which is encoded by a nucleic acid sequence that has at least 80% identity with SEQ ID NO: 8. In particular, the HAS is a chlorella virus polypeptide. A nucleic acid segment encoding the HAS is also provided, which nucleic acid segment is used in the preparation of recombinant cells which produce hyaluronate synthase and its hyaluronic acid product. Hyalurante is also known as hyaluronic acid or hyaluronan.
INTERVENANTS
Déposant
UNIV OKLAHOMA (THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA) - US
Titulaire
The Board of Regents of The Unive
Inventeur
WEIGEL PAUL H (WEIGEL, PAUL, H.) - US
KUMARI KSHAMA (KUMARI, KSHAMA) - US
DEANGELIS PAUL (DEANGELIS, PAUL) - US
Mandataire
CABINET WEINSTEIN - 176 AVENUE CHARLES DE GAULLE - 92201 NEUILLY SUR SEINE - FR - N° Siren : 334924149
STATUT EN FRANCE : Dossier expiré
Délivrance
15/12/2004
Remise de traduction du brevet
04/11/2005 (BOPI 2005-44)
Dernière annuité payée
27/10/2017
Quantième- N° de l'annuité payée
20